What does it actually take to build a quantum computer that can scale to millions of qubits?
Learn more about Qolab here: https://qolab.ai/
In this episode, we speak with John Martinis, recipient of the 2025 Nobel Prize in Physics. Martinis is a pioneer in superconducting quantum computing and led the team of engineers at Google Quantum AI during the development of their Sycamore chip, which was the first to demonstrate “Quantum Supremacy,” the outperformance of a quantum computer compared to a classical supercomputer.
John is now the co-founder of Qolab, a company developing new approaches to building scalable superconducting quantum circuits. Martinis discusses why scaling quantum computers is fundamentally an engineering and manufacturing problem, and why the next generation of quantum hardware may require rethinking how the chips themselves are designed and fabricated.
We explore the challenges of building superconducting qubits, from fabrication and packaging to control electronics, wiring, power dissipation, and the subtle imperfections that can determine whether a quantum chip works at all. Martinis explains why adding more qubits is not simply a matter of making existing systems larger. At the scale of hundreds of thousands or millions of qubits, every component has to work together, and improvements in one part of the system can create new problems somewhere else.
Martinis describes the philosophy behind Qolab and its effort to develop a fundamentally different architecture for scalable quantum computing. Rather than simply pushing existing approaches forward, Qolab is trying to remake the individual elements of the system and integrate them in new ways. We discuss wafer-scale fabrication, the challenges of connecting and controlling large numbers of superconducting qubits, and why the manufacturing techniques used to build modern semiconductor chips could be important for the future of quantum computing.
We also discuss the practical engineering lessons Martinis learned while developing superconducting quantum processors, including the difficulty of getting an entire system to work reliably. He recounts the development of the hardware behind Google's early quantum computing efforts, the unexpected failure caused by a circuit board rather than the qubit chip itself, and the many subtle fabrication and engineering issues that can become increasingly important as quantum systems grow larger.
Finally, Martinis explains why he sees quantum computing as a system engineering problem involving dozens of interconnected constraints. From the physics of superconducting qubits to semiconductor fabrication, cryogenic electronics, packaging, and control, building a useful quantum computer requires solving many problems simultaneously. The goal is not simply to build a better qubit, but to develop an architecture that can ultimately support quantum computers at truly large scale.
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Timestamps:
00:00 - Intro
01:06 - Secrecy of Fabrication
03:24 - 2 Qubit Gate with Transmons
05:18 - New Knowledge of Superconducting Quantum Computers
08:53 - What are Transmons?
35:56 - Lessons from Failure
38:05 - The Role of Theory in Martinis’ Work
44:51 - Two Level States
48:15 - Engineering Tricks in Superconducting Quantum Computers
53:32 - Metrics for Quantum Success
1:00:11 - Scaling Quantum Computers
1:08:08 - Identifying Sources of Error
1:16:15 - Quantum Supremacy Experiment
1:25:45 - What If Quantum Mechanics Failed?
1:33:10 - Is Quantum Supremacy Holding Up?
1:34:42 - Lift-off Fabrication for Superconducting Quantum Computers
1:41:59 - Quantum Flexibility vs Foundries
1:43:40 - Connecting Distant Qubits
1:47:41 - Codesign for Fault-Tolerance
1:49:16 - Martinis’ Nobel Prize
2:01:55 - Advice for Young Scientists
#quantumcomputing #quantumphysics #superconductor #nobelprize #fabrication
